LÓPEZ VIDAL MARTÍN GUILLERMO
Artículos
Título:
Thiol-free chemoenzymatic synthesis of β-ketosulfides
Autor/es:
HEREDIA, ADRIÁN A; LÓPEZ-VIDAL, MARTÍN G; KURINA-SANZ, MARCELA; BISOGNO, FABRICIO R; PEÑÉÑORY, ALICIA B
Revista:
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Editorial:
BEILSTEIN-INSTITUT
Referencias:
Lugar: Frankfurt; Año: 2019 vol. 15 p. 378 - 378
ISSN:
1860-5397
Resumen:
preparation of β-ketosulfides avoiding the use of thiols is described. The combination of a multicomponent reaction and a lipasecatalysed hydrolysis has been developed in order to obtain high chemical diversity employing a single sulfur donor. This methodology for the selective synthesis of a set of β-ketosulfides is performed under mild conditions and can be set up in one-pot two-stepand on a gram-scale.
