Strategies for finishing physical maps of macro-DNA regions

CANTOR C.R.; SMITH C.L.; ARGARAÑA C.E.; OI LIAN KON

Integration and Control of Metabolic Processes: Pure and Applied Aspects

ICSU and Cambridge Univ Press

Año: 1987; p. 427 - 438

The new technology for handling large DNA molecules has greatly facilitated our ability to make restrictions maps of mega-base regions o DNA. It is relatively easy to start such a map for any region of interest for which cloned DNA probes are available, but it is relatively difficult.................