Novel Potential nanostructures for photodynamic therapyrtame

PABLO F. GARCÍA; LUIS PÉREZ; EDUARDO CORONADO ; ARGÜELLO, GERARDO ANÍBAL

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2015 vol. 12

imers could be very effective for generating photothermal damage because theexcitation of the surface plasmon resonance (SPR) results in a temperature increasenear the NP surface. In addition they present the advantage that the frequency of theSPR resonance can be tuned by using different NPs sizes or interparticle eparations. The surface enhanced Raman scattering (SERS) response of the complex located in the gap of the NP aggregates results in an analytical SERS enhancement factor of 100,000. This feature corroborates that the ruthenium complex is indeed located betweennanoparticles. An additional confirmation of this fact has been performed usingTransmission Electron Microscopy (TEM), in which dimers, trimers and otheraggregates where found. A kinetic study of the NP aggregation process, followed by the evolution of the UV vis extinction spectra, has been also performed. The results show that in a first stage it exist isolated NPs, later we can see the formation of dimers and trimer