Synthesis, antiprotozoal and cytotoxic activities of N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino derivatives

Elsevier

Año: 2004 vol. 59 p. 431 - 431

font size="1" face="Times-Roman"> Three derivatives of N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino (1), a compound which exhibits significant activity against Trypanosoma cruzi and Plasmodium falciparum but with cytotoxicity toward murine L-6 cells, were syn