Dissolution kinetics and mechanism of Mg-Al layered hydroxides: A simple approach to describe drug release in acid media

MARA PARELLO; RICARDO ROJAS; CARLA E. GIACOMELLI

ACADEMIC PRESS INC ELSEVIER SCIENCE

Año: 2010 vol. 351 p. 134 - 134

font size="1" face="AdvGulliv-R"> Layered double hydroxides (LDHs) weathering in acidic media is one of the main features that affects their applications in drug delivery systems. In this work, the dissolution kinetics of biocompatible Mg–Al LDHs was studied at different initial pH values and solid concentrations using a simple and fast experimental method that coupled flow injection analysis and amperometric detection. A carbonate intercalated sample