GIACOMELLI CARLA EUGENIA
Congresos y reuniones científicas
Título:
Smaller is better: microfluidics meet surfaces
Autor/es:
CARLOS D. GARCIA; MARIA F. MORA; CARLA E. GIACOMELLI; J. WEHMEYER; R. BIZIOS; A. A. AYON
Lugar:
Reno (EE.UU)
Reunión:
Congreso; 35th FACSS Conferences; 2008
Resumen:
Since their initial development, capillary electrophoresis microchips (uchip-CE) have shown a tremendous improvement in their capabilities to deal with real samples. In this regard, rapid, inexpensive and sensitive detection methods are absolutely necessary to achieve the goal of a true point-of-care testing device. In conjunction with microchips, electrochemical detection (ECD) is particularly attractive because of its analytical performance, versatility, and compatibility with microfabrication procedures. Considering the hypothesis that simple surface modifications in surface chemistry would produce significant improvements in the performance of uchip-CE-ECD, the most recent results from our lab will be discussed in this presentation. Along with basic background information, the effects of dynamic coatings on the separation and on electrochemical detection at the microchip scale will be discussed. Then, two strategies to integrate enzyme reactors and biosensors to the microchip will be presented