NON-TYPICAL LEAVING GROUPS IN VISIBLE LIGHT PHOTOCATALYZED C-H FUNTIONALIZATION REACTIONS

Cologne

Simposio; 20th European Symposium on Organic Chemistry; 2017

Aryl radicals are important intermediates in organic synthesis and these could be obtained by visible light photoinduced electron transfer (PET) from catalysts. However, in classical approach only electron deficient arenes, such as diazonium salts or some aryl iodides could be used, which is explained by the accessible reducing power of typical visible light photoredox catalysts. In this work we explore a conPET approach using substrates with non-typical leaving groups such as Ar-NR3+X- and alcohols for the functionalization of heterocycles poorly explored in visible light photoredoxcatalysis. Then amines and ?OR are used as leaving groups allowing a more straightforward substitution of alcohols and amines.