In this work, a synthetic pathway was developed to obtain dendritic molecule-coated magnetic nanoparticles. Figure 1 shows the synthetic strategy used. Briefly, maghemite magnetic iron oxide (g-Fe₂O₃) nanoparticles NPs were modified with 3-(aminopropyl)trimethoxysilane (APS) as silane coupling agent [7].  Afterwards, dendritic molecule (D NO₂) were covalently attached to the modified NPs, achieving nitro-functionalized magnetic nanoparticles. Infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), and transmission electronic microscopy (TEM) were used to characterize the derivatised surface.