N-Substitution of Saccharin in Solid-Liquid Phase-Transfer Conditions. B. Arguello, A. R. Suárez y M. Fumarola

C. PÉREZ; E. CALANDRI; M. R. MAZZIERI; B. ARGUELLO; A. R. SUÁREZ ; M. FUMAROLA

ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD

Año: 1984 vol. 16 p. 37 - 37

p style="TEXT-INDENT: 0cm; MARGIN: 0cm 0cm 0pt" class="MsoNormal">The present paper reports the successful synthesis of N-alkyl and N-acyl derivatives of saccharin. This was carried out by reaction of sodium saccharin with alkyl or acyl halides in toluene. The catalyst was tetrabutylammonium bromide under phase-transfer conditions.