Hydrophobicity estimations of benzenesulfonamidofluoroquinolones (BSFQs) by RP-LC. Influence of chromatographic parameters in QSAR studies

NIETO M. J. ; RODRIGUEZ-MANZANARES P. A; MANZO R. H; MAZZIERI M. R.

BIRKHAUSER BOSTON INC

Lugar: Boston; Año: 2003 vol. 12 p. 94 - 94

p style="TEXT-INDENT: 0cm; MARGIN: 0cm 0cm 0pt 15.9pt; BACKGROUND: white" class="MsoNormal">Reversed-phase chromatographic parameters of new Benzenesulfonamide fluoroquinolones (BSFQs) were determined to evaluate their use in QSAR analysis. High correlation among CLogP, log kw, and RMw, and between Alog kw or ÄRMw with Hansc