Controlling stereochemistry in C-C- and C-H bond formation with electronically asymmetric organimetallics and chiral poisons

J.W. FALLER; M.R. MAZZIERI; J.T. NGUYEN; J. PARR; M. TOKUNAGA

INT UNION PURE APPLIED CHEMISTRY

Año: 1994 vol. 66 p. 1463 - 1463

ir stable (cyclopentadienyl)Mo(NO)(halide)(q3-allyl) complexes add to aldehydes to yield homoallylic alcohols in high enantioselectivity and diastereoselectivity. A new strategy, chiral poisoning, is applied to asymmetric hydrogenation and the kinetic resolution of allylic alcohols using transition metal catalysts prepared from racemic bis-phosphine ligands.