Cruzipain a major Trypanosoma cruzi cystein protease in host-parasite interplay

GEA S; GUIÑAZU N; PELLEGRINI A; CARRERA EA; GIORDANENGO L; CANO R; AOKI MP

INMUNOLOGIA

Lugar: Madrid; Año: 2006 p. 225 - 225

0213-9626

nbsp; Protozoan parasite Trypanosoma cruzi, etiological agent of Chagas disease, is endemic in Central and South America and produce the most common myocarditis worldwide. Parasite persistence eventually leads to a debilitating heart disease that kills more than 50,000 people every year. There is no consensus as to whether tissue damage is caused entirely by the parasite or is exacerbated by an autoimmune response. In both models of disease progression, cruzipain- the maj