Aphrodisiac activity of Phlegmariurus saururus in copulating and noncopulating male rats

BIRRI, MARCELA; VALLEJO, MARIANA; CARRO-JUÁREZ, MIGUEL; AGNESE, ALICIA MARIEL

PHYTOMEDICINE

ELSEVIER GMBH

Año: 2017 vol. 24 p. 104 - 104

0944-7113

ackground Phlegmariurus saururus is popularly known in Argentina as aphrodisiac. For this reason, it was previously investigated and determined that the decoction of this plant elicits pro-ejaculatory activity and increases the ejaculatory potency in the Fictive Ejaculation Model. Hypothesis/Purpose the decoction of P. saururus facilitates sexual behavior in sexually experienced male rat and induces copulatory behavior in non-copulating male rats. Methods The extraction method (decoction) was validated through Selectivity, Accuracy and Precision, by identification of the majority alkaloids, expressed as sauroxine. Male (sexually experienced and noncopulating) and female (receptive) Wistar rats were used to determine sexual behavior. Sildenafil was used as positive control. The following variables were evaluated: Mount Latency, Intromission Latency, Ejaculation Latency, Post Ejaculatory Interval, as well as the Mounts and Intromissions Number. Results In sexually experienced male rats,