Synthesis and Properties of Dendronized Chitosan

AGUSTINA ALDANA; MARISA MARTINELLI; MIRIAM STRUMIA

WISLEY

Año: 2010 vol. 298 p. 99 - 99

font face="AdvP3D133F" color="#231f20" size="2"> Chitosan films and microspheres were prepared and their surfaces were functionalized with first generation dendritic molecules. The films were modified by Weisocyanate dendron, while Behera’s and bis Behera’s amine dendrons were used to modify the microspheres. Prior to dendronization films were prepared by blending chitosan with 18% of polyvinyl pyrrolidone (PVP), and casting the resulting mixture. The degree of dendronization reached was 28%. The microspheres were prepared by coacervation/precipitation, after which the surfaces were activated with either epychlorohydrine (ECH) or 1,4-butanediol diglycidyl ether (BDGE). The oxirane groups were utilized to form covalent bonds between chitosan and dendrons. The degree of dendronization