Artículos
Título:
- Synthesis of macroporous polymers with radical scavenging properties by immobilization of polyphenolic compounds.
Autor/es:
DARIO ARRUA; JUAN F. BASBUS; MIRIAM STRUMIA; CECILIA ALVAREZ; MÓNICA NAZARENO
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2012 vol. 72 p. 807 - 807
Resumen:
olid phase radical scavengers have been prepared by the immobilization of antioxidant (AOX) compounds
on macroporous polymers. Poly(glycidylmethacrylate-co-trimethylolpropane trimethacrylate)
[poly(GMA?TRIM)] and poly(N-acryloyl-tris(hydroxymethyl)aminomethane-co-glycidylmethacrylateco-
N,N0-methylenebisacrylamide) [poly(NAT?GMA?BIS)] were prepared by free radical polymerization
using a mixture of dimethylsulfoxide (DMSO)-poly(ethyleneglycol) 6000 (PEG 6000) as a porogenic solvent.
The polymers were aminated with ethylenediamine (EDA) and the linkage of the polyphenolic compounds
(gallic and caffeic acids) was carried out by two different approaches: through N,N0-
dicyclohexylcarbodiimide/4-dimethylaminepyridine (DCC/DMAP) system (one-step method) or through
the previous formation of the acyl chloride of the polyphenolic compounds and subsequent amidation
reaction (two-step method). The available phenolic groups on the macroporous polymers were determined
using the Folin?Cio