Design, Synthesis and Architectures of Hybrid Nanomaterials for Therapy and Diagnosis Applications

MACCHIONE, MICAELA; BIGLIONE, CATALINA; STRUMIA, MIRIAM

Polymers

MDPI

Lugar: Berna; Año: 2018 vol. 10 p. 2 - 2

2073-4360

bstract: Hybrid nanomaterials based on inorganic nanoparticles and polymers are highly interestingstructures since they combine synergistically the advantageous physical-chemical properties ofboth inorganic and polymeric components, providing superior functionality to the final material.These unique properties motivate the intensive study of these materials from a multidisciplinary viewwith the aim of finding novel applications in technological and biomedical fields. Choosing a specificsynthetic methodology that allows for control over the surface composition and its architecture,enables not only the examination of the structure/property relationships, but, more importantly,the design of more efficient nanodevices for therapy and diagnosis in nanomedicine. The currentreview categorizes hybrid nanomaterials into three types of architectures: core-brush, hybrid nanogels,and core-shell. We focus on the analysis of the synthetic approaches that lead to the formation of eachtype of archite