pH-induced changes in the fabrication of multilayers 1 of poly(acrylic acid) and chitosan: fabrication, properties and test as drug storage and delivery system.

EDUARDO GUZMAN; JESICA CAVALLO; RAQUEL CHULIÁ-JORDÁN; CESAR G. GOMEZ; MIRIAM STRUMIA; FRANCISCO ORTEGA ; RAMÓN G. RUBIO

AMER CHEMICAL SOC

Año: 2011 vol. 27 p. 6835 - 6835

font size="2" face="AdvOT2e364b11"> Multilayers of poly(acrylic acid), PAA, and chitosan, CHI, have been built by the layer-by-layer (LbL) method from aqueous solutions at different pH values and analyzed by the dissipative quartz crystal microbalance (D-QCM) and ellipsometry. The results showed that under all of the assembly conditions considered the growth of the films is nonlinear. The thickness of the PAA layers increases as the pH of the assembling solutions decreases,