Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters.

FACUNDO MATTEA; MARCELO ROMERO; JOSÉ VEDELAGO; ANDRES QUIROGA; MAURO VALENTE; MIRIAM STRUMIA

PERGAMON-ELSEVIER SCIENCE LTD

Lugar: Amsterdam; Año: 2015 vol. 100 p. 101 - 101

olymer geldosimetershavespecific advantagesforrecording3Dradiationdosedistributionindiag- nostic andtherapeuticmedicalapplications.But,eveninsystemswherethe3Dstructureisusually maintained forlongperiodsoftimeafterirradiation,itisstillnotpossibletoeliminatethediffusionof the differentspeciesintheregionsofdosegradientswithinthegel.Asaconsequence,informationofthe dose losesqualityovertime.Inthepursuitofasolutionandtoimprovetheunderstandingofthis phenomenon anovelsystembasedonitaconicacidandN-N′-methylene-bisacrylamide(BIS)ishereby proposed. Effectsofchangesinthechemicalstructureofthemonomersoverthedosimetricsensitivity and overthepost-irradiationdiffusionofspecieswasstudied.Inthisstudy,oneofthecarboxylicgroups of theitaconicacidmoleculewasmodified withanilinetoobtainmoleculeswithsimilarreactivitybut different molecularsizes.Then,dosimetersbasedonthesemodified speciesandontheoriginalITA molecules wereirradiatedinanX-raytomographyapparatusatdifferentdosesupto173Gy.Afterward