Analytical and rheological studies of modified gel dosimeters exposed to X-ray beams

MARCELO ROMERO; FACUNDO MATTEA; JOSE VEDELAGO; DAVID CHACÓN; MAURO VALENTE; CECILIA ALVAREZ I.; MIRIAM STRUMIA

MICROCHEMICAL JOURNAL

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2016 vol. 127 p. 231 - 231

0026-265X

he need to know the dose of X-rays to be applied to patients suffering diseases such as cancerrequires accurate and stable dosimetric devices. Currently, the use of gelatin-based dosimetershas yielded excellent results but lack adequate thermal stability. In this paper a chemicalmodification of the gelatin (at concentrations typically used for the preparation of dosimeters)using glutaraldehyde as a cross-linking agent is proposed. Through rheological studies it wasfound that modified gelatin with glutaraldehyde concentrations between 0.15 and 0.50 % w / vshow better thermal stability with an increase in elastic modulus of up to 100 times at 37°C andconvenient reaction times for the preparation of the dosimeters. Subsequently, a mathematicalmodel to easily predict the elastic modulus of materials prepared with different concentrationsof gelatin and glutaraldehyde was proposed. The analytical response of modified andunmodified materials was evaluated and no significant alteration of the