Rheological, Dielectric and Diffusion Analysis of Mucin/Carbopol Matrices used in Amperometric Biosensors

RAÚL CAPRA; ANA BARUZZI; LIDIA QUINZANI; MIRIAM STRUMIA

Sensors and Actuators B: Chemical

Año: 2007 p. 466 - 466

h3 style="MARGIN: 6pt 0cm 0pt">Abstract The performance of enzymatic biosensors is highly dependent on the immobilization conditions of the enzyme. Immobilizing oxalate oxidase in a mucin /carbopol gel results in an amperometric electrode for oxalate sensing, with high stability and a much longer linear range than with albumin as support polymer. By way of a comparative analysis, we show in this paper how the physicochemical properties of the support may contribute to determine the analytical response of this type of sensor.  Matrices based in mucin, carbopol, blends of mucin and carbopol, and albumin, all slightly crosslinked with glutaraldehyde, were analyzed. The swel