Chemical Overview of Gel Dosimetry Systems: A Comprehensive Review

MACCHIONE, MICAELA; SOFÍA LECHON PAEZ; MIRIAM STRUMIA; MAURO VALENTE; FACUNDO MATTEA

Gels

MDPI

Lugar: Basel; Año: 2022 vol. 8 p. 663 - 663

2310-2861

bstract: Advances in radiotherapy technology during the last 25 years have significantly improvedboth dose conformation to tumors and the preservation of healthy tissues, achieving almost realtimefeedback by means of high-precision treatments and theranostics. Owing to this, developinghigh-performance systems capable of coping with the challenging requirements of modern ionizingradiation is a key issue to overcome the limitations of traditional dosimeters. In this regard, a deepunderstanding of the physicochemical basis of gel dosimetry, as one of the most promising toolsfor the evaluation of 3D high-spatial-resolution dose distributions, represents the starting point fordeveloping new and innovative systems. This review aims to contribute thorough descriptions of thechemical processes and interactions that condition gel dosimetry outputs, often phenomenologicallyaddressed, and particularly formulations reported since 2017.