Dissociation of TSH-dependent enzyme activities, reduced iodide transport and preserved iodide organification in non-functioning thyroid adenoma and multinodular goiter

MASINI ANA,; ANA MARIA DE LOS A. CABANILLAS; BONATERRA MONICA,; COLEONI ALDO,

JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM

Endocrine Society

Año: 1994 vol. 79 p. 39 - 39

0021-972X

p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt">Several biochemical and functional modifications demonstrated in goitrous tissues could reflect the effect of goitrogenic factors. Growthenhancing agents, including TSH itself, have been involved in goitrogenesis. To study comparatively the variation patterns of some TSHdependent enzymes within single goitrous tissues, we measured the activ