Nitric oxide/cGMP signalling inhibits TSH-stimulated iodide uptake and

BAZZARA, LEONARDO; VELEZ, MARIA LAURA; COSTAMAGNA, MARIA; CABANILLAS, ANA MARIA; FOZZATTI, LAURA; LUCERO, ARIEL; PELLIZAS, CLAUDIA; MASINI-REPISO, ANA

MARY ANN LIEBERT

Lugar: NEW ROCHELLE, NY, USA; Año: 2007 vol. Aug p. 717 - 717

b> Objective: Nitric oxide (NO) induces morphological and functional alterations in primary cultured thyroid cells. The aim of this paper was to analyze the direct influence of a long-term exposition to NO on parameters of thyroid hormone biosynthesis in FRTL-5 cells.Nitric oxide (NO) induces morphological and functional alterations in primary cultured thyroid cells. The aim of this paper was to analyze the direct influence of a long-term exposition to NO on parameters of thyroid hormone biosynthesis in FRTL-5 cells. Design: Cells were treated with the NO donor, sodium nitroprusside (SNP) for 24?72h.Cells were treated with the NO donor, sodium nitroprusside (SNP) for 24?7