Early events associated to the oral coadministration of type II collagen and chitosan: induction of anti-inflammatory cytokines

CARINA PORPORATTO,; ISMAEL BIANCO,; ANA MARIA DE LOS A. CABANILLAS; SILVIA CORREA,

Oxforf University Press

Lugar: LONDON; Año: 2004 vol. 16 p. 433 - 433

p style="MARGIN: 0cm 0cm 0pt; mso-layout-grid-align: none" class="MsoNormal">Oral administration of an antigen can result in local and systemic priming or tolerance and the basis of this dichotomy is poorly understood. The intestinal microenvironment, and factors such as nature of the antigen, dose, genetic background, uptake and concentration of the antigen that