Synthesis of ultraluminescent gold core-shell nanoparticles as nanoimaging platforms for biosensing applications based on metal-enhanced fluorescence

D. GONTERO; ALICIA V. VEGLIA; A. G. BRACAMONTE; D. BOUDREAU

RSC Advances

Royal Society of Chemistry

Lugar: Londres; Año: 2017 vol. 7 p. 10252 - 10252

ore shell nanoparticles are versatile nanostructures that can be used as luminescent biosensing platformsin many nanotechnological developments. Ultraluminescent fluorescent gold core?shell nanoparticlesbased on Metal-Enhanced Fluorescence (MEF) were synthesized. The nanoparticles obtained wereformed by 40.0 nm cores and variable silica spacer lengths. Silica spacer lengths from 6.0 to 25.0 nmwere obtained. The plasmon maximal wavelength of the core?shell nanoparticles was shifted to a longerwavelength from a gold nanoparticle plasmon centered at 537.0 nm to 545.0 nm and 548 nm from6.0 nm to 20.0 nm spacer length, respectively. The effect of the gold core on emission was evaluated bydetermination of Metal Enhanced Fluorescence enhancement factors (MEFef), applying the sodiumcyanide method for core leaching. We observed maximal MEF ef= 8.1 and 7.2 for 6.0 and 14.0 nm,respectively, and a significant decrease at longer silica spacer lengths. From nanoimaging by confocalfluorescence micro