Biphasic Approach for the Synthesis of Au Nanoparticles via Diffusional Release of Gallic Acid from Supramolecular Hydrogels to Aqueous Solutions: Implications for Biomedical Applications

SERGIO D. GARCÍA SCHEJTMAN; PABLO A. MERCADAL; MATÍAS L. PICCHIO; ALICIA V. VEGLIA; EDUARDO A. CORONADO

ACS Applied Nano Materials

ACS

Año: 2023 vol. 6 p. 7259 - 7259

wing to the unique optical and chemical properties of plasmonicnanoparticles, new synthetic approaches for their fabrication are constantly beingdeveloped to control their size, shape, colloidal stability, and surfacefunctionalization. This work presents a biphasic method based on the controlledrelease of a reducing agent from a supramolecular polymer hydrogel to producegold nanoparticles (Au NPs). Specifically, Au NPs are obtained by gallic acid(GA) diffusion from a poly(vinyl alcohol) (PVA)/GA hydrogel to a Au3+solution using the reducing properties of polyphenols. The formation processof Au NPs is investigated under different conditions, such as changing the PVA/GA stochiometric ratio and Au3+ concentration. It is demonstrated that a subtlechange in the conditions leads to different Au NPs sizes and morphologies. Au NPs of small size can be obtained (