WHAT DO WE NEED TO LEARN TO OPTIMIZE THE SLIT ALTERNATIVE?

SERRA, HORACIO MARCELO; ALIGNANI, D.O; PASSALACQUA, G; CANONICA, G.W; CORREA, S.G

European annals of allergy and clinical immunology

Año: 2006 vol. 38 p. 158 - 158

p style="margin: 0cm 0cm 0pt; line-height: 150%; text-align: justify;" class="MsoNormal">Allergen-specific immunotherapy (IT) is the only treatment of allergy in adults and children capable of modifying the immune response at early steps. As a consequence, IT improves symptoms, prevents the onset of new sensitizations, reduces the risk of developing asthma and its clinical efficacy lasts many years. The main rationale for administering sublingually IT (SLIT) is to reduce the occurrence of side effects, still yet preserving the immunological effects.  SLIT with the most common allergens have been used in many studies with significant clinical effectiveness in both asthma and rhinitis.