ADMINISTRATION OF A PEPTIDE INHIBITOR OF ALPHA-4 INTEGRIN INHIBITS THE DEVELOPMENT OF EXPERIMENTAL AUTOIMMUNE UVEITIS.

P. MARTÍN, ANDREA; VIEIRA DE MORAES, LUCIANA; E. TADOKORO, CARLOS; G. COMMODARO, ALESSANDRA; ENRIQUE URRETS-ZAVALIA,; A. RABINOVICH, GABRIEL; JULIO URRETS-ZAVALIA,; V. RIZZO, LUIZ; SERRA, HORACIO MARCELO

ASSOC RESEARCH VISION OPHTHALMOLOGY INC

Año: 2005 vol. 46 p. 2056 - 2056

b> PURPOSE. Recruitment of lymphocytes into the retina and to the vitreous during the development of experimental autoimmune uveitis (EAU) is governed by factors such as the state of activation of inflammatory cells and the repertoire of adhesion molecules expressed by the local vascular endothelia. 4 Integrins and their receptors play an important role during homing of cells to the inflammatory site. In the pr