IMPACT OF CHANGING OXYGENATION POLICIES ON RETINOPATHY OF PREMATURITY IN A NEONATAL UNIT IN ARGENTINA

JA URRETS-ZAVALIA,; CRIM N; EG KNOLL,; F. ESPOSITO,; ELIZABETH COLLINO; URRETS ZAVALIA ME; SAENZ-DE-TEJADA G; JUAN I. TORREALDAY; SERRA HM; GILBERT C

BRITISH JOURNAL OF OPHTHALMOLOGY

BMJ Group

Año: 2013 vol. 96 p. 1456 - 1456

1468-2079

ims: To assess the impact of different oxygenation policies on the rate and severity of retinopathy of prematurity (ROP). Methods: Between January 2003 and December 2006, infants of 1500 g birthweight (BW) or less and/or 32 weeks gestational age (GA) or less, and larger, more mature infants with risk factors for ROP were examined through three different time periods: period 1: high target oxygen saturation levels (88?96%) and treatment at threshold ROP; period 2: low target oxygen saturation levels (83?93%) and treatment at threshold ROP; period 3: low target oxygen saturation and treatment at type 1 ROP. Results: Type 1 ROP was detected more frequently in babies of 32 weeks GA or less (50/365, 13.7%) than in more mature babies (15/1167, 1.3%; p<0.001). The rate of type 1 ROP in period 1 was 6.9%; period 2, 3.6% and period 3, 1.8%. Rates of stage 3 ROP declined over time in both BW/GA groups ( from 9.0% to 4.1% to 2.0%) as did rates of plus disease ( from 7.5% to