PROTEIN PROFILE IN PTERYGIUM TISSUE FROM PATIENTS WITH INDOOR ACTIVITIES.

MARIA F. SUAREZ; PIQUERAS CARMEN; ALGECIRAS M; BHATTACHARYA SK; SERRA H.M

Academia Journal of Scientific Research

Academia Publishing.

Año: 2021

2315-7712

terygium, commonly called “surfer’s eye”, is an ocular surface disease characterized by an abnormal wing-shaped growth of epithelial and fibro vascular tissue in the corneoscleral limbus that centripetally invades the cornea, significantly distorting the surface of the eye, and initiate astigmatism and blockage of the visual axis. It is usually manifested among populations with a high exposure to ultraviolet radiation (UVR). Given that pterygium also occurs in people with normal UVR contact, we performed this study in order to determine the differential proteomic profiling between advanced pterygium from patients with normal exposure to UVR and normal conjunctiva specimens using a mass spectrometry approach. We additionally discussed our results with previous report performed with pterygium specimens from patients with high exposure to UVR. Conjunctival tissues from pterygium and healthy conjunctiva were obtained by the same surgeon from patients with pterygium in an advanced stage th