SERRA HORACIO MARCELO
Capítulos de libros
Título:
CORNEAL ANTI OXIDATIVE MECHANISMS MALFUNCTION ARE INVOLVED IN THE GENESIS OF CLIMATIC DROPLET KERATOPATHY
Autor/es:
M FERNANDA SUAREZ; HORACIO M. SERRA; NONE
Libro:
Top 10 Contributions on Ophthalmology
Editorial:
Avidscience
Referencias:
Año: 2019; p. 1 - 31
Resumen:
disease of unknown etiology. We described CDK for the first time
in Latin America in the Argentinean Patagonia (El Cuy). A deeper
knowledge of CDK pathogenic mechanisms will provide new therapeutic
strategies. For that reason we investigated the prevalence of
CDK in El Cuy and its existence in other 3 provinces with similar climate.
Patients eye were exanimate, inquired about habits throughout
lives and serum ascorbate (sAA) determined. All individuals work
outdoors for most of the day. All regions had normal O3 levels. Individuals
from regions 1, 2, and 3 had very low consumption of vegetables/
fruits and low sAA levels. Conversely, region 4 individuals had
balanced diet and higher sAA concentrations. CDK was only found
in region 3 where individuals had partial deficiency of sAA and did
not use eye protection.
No CDK was found in regions 1 and 2 where individuals had
similar work activities and dietary habits to those in region 3 but wear
eye protection. No disease was found in region 4 where individuals
work outdoor, have balanced diet and use eye protection. To summarize,
the CDK existence was not only related to climate but also to the
dietary habits and lack of protection to sunlight.
in Latin America in the Argentinean Patagonia (El Cuy). A deeper
knowledge of CDK pathogenic mechanisms will provide new therapeutic
strategies. For that reason we investigated the prevalence of
CDK in El Cuy and its existence in other 3 provinces with similar climate.
Patients eye were exanimate, inquired about habits throughout
lives and serum ascorbate (sAA) determined. All individuals work
outdoors for most of the day. All regions had normal O3 levels. Individuals
from regions 1, 2, and 3 had very low consumption of vegetables/
fruits and low sAA levels. Conversely, region 4 individuals had
balanced diet and higher sAA concentrations. CDK was only found
in region 3 where individuals had partial deficiency of sAA and did
not use eye protection.
No CDK was found in regions 1 and 2 where individuals had
similar work activities and dietary habits to those in region 3 but wear
eye protection. No disease was found in region 4 where individuals
work outdoor, have balanced diet and use eye protection. To summarize,
the CDK existence was not only related to climate but also to the
dietary habits and lack of protection to sunlight.
