Preliminary evaluation of the in vivo antigenic power of a new formulation for the bovine babesiosis immunoprophylaxis Evaluación preliminar del poder antigénico in vivo de una nueva formulación para la inmunoprofilaxis de la babesiosis bovina

DEL RÍO ÁLVAREZ, F.R.; PEICHOTO, M.E.; PALMA, S.; MALETTO, B.; LOZINA, L.

Revista Veterinaria

Universidad Nacional de Nordeste (UNNE)

Año: 2022 vol. 33 p. 266 - 266

1668-4834

ovine babesiosis is a hemoparasitic disease caused by protozoa of the genus Babesia, the most important are Babesia bovis and B. bigemina, both transmitted by the common bovine tick, Rhipicephalus microplus. In combination with anaplasmosis, they form the Bovine Tristeza Complex, one of the main limiting factors for productive development in tropical and subtropical areas of the world. Currently, for the prophylaxis of bovine babesiosis in Argentina, only live vaccines are available in fresh and deep-frozen presentations. In the present work, we evaluated the immunogenicity of erythrocytes parasitized with Babesia sp, dehydrated and incorporated into a new adjuvant, formulated for use in humans, as a new immuno prophylactic alternative. With this aim, parasitized erythrocytes obtained from in vitro cultures were dehydrated by spray-drying techniques and assembled with an adjuvant. Twelve calves negative for blood parasites were used, which were divided into 4 groups of 3 animals each