MRSA dynamic circulation between the community and the hospital setting: new insights from a cohort study in Argentina

DANILO BARCUDI; EZEQUIEL J. SOSA; RICARDO LAMBERGHINI; ANALÍA GARNERO; DARIO TOSORONI; LAURA DECCA; LILIANA GONZALEZ; MARÍA A. KUYUK; TERESA LOPEZ; IVANA HERRERO; PAULO CORTES; MYRIAN FIGUEROA; ANA L. EGEA; PAULA GAGETTI; DARÍO A. FERNANDEZ DO PORTO; STUDY GROUP OF S. AUREUS IN CÓRDOBA; ALEJANDRA CORSO; ADRIÁN G. TURJANSKI; JOSÉ LUIS BOCCO; CLAUDIA SOLA

THE JOURNAL OF INFECTION.

W B SAUNDERS CO LTD

Lugar: Londres; Año: 2020 vol. 80 p. 24 - 24

0163-4453

issemination of methicillin-resistant-Staphylococcus aureus/(MRSA) is a worldwide concern both in hospitals [healthcare-associated-(HA)-MRSA] and communities [community-associated-(CA)-MRSA]. Knowledge on when and where MRSA colonization is acquired and what clones are involved is necessary, to focus efforts for prevention of hospital-acquired MRSA-infections.Methods A prospective/longitudinal cohort study was performed in eight Argentina hospitals (Cordoba/October-December/2014). Surveillance cultures for MRSA (nose-throat-inguinal) were obtained on admission and at discharge. MRSA strains were genetically typed as CA-MRSAG and HA-MRSAG genotypes. Results Overall, 1419 patients were screened and 534 stayed at hospital for ≥3 days. S. aureus admission prevalence was 30.9% and 4.2% for MRSA. Overall MRSA acquisition rate was 2.3/1000 patient-days-at-risk with a MRSA acquisition prevalence of 1.96% (95%CI: 1.0%-3.4%); 3.2% of patients were discharged back to community with MRSA. C