Different evolution of S. aureus methicillin-resistant and methicillin-susceptible infections, Argentina

BARCUDI, DANILO; BLASKO, ENRIQUE; GONZALEZ, MARÍA JOSÉ; GAGETTI, PAULA; LAMBERGHINI, RICARDO; GARNERO, ANALÍA; SARKIS, CLAUDIA; FACCONE, DIEGO; LUCERO, CELESTE; TOSORONI, DARIO; BOCCO, JOSÉ L.; CORSO, ALEJANDRA; SOLA, CLAUDIA

Heliyon

Elsevier Ltd

Lugar: Londres; Año: 2023 vol. 10

2405-8440

taphylococcus aureus-(SA) is widespread among healthcare-associated-(HA) and the community-associated-(CA) infections. However, the contributions of MRSA and MSSA to the SA overall burden remain unclear. In a nationally-representative-survey conducted in Argentina, 668 SA clinical isolates from 61 hospitals were examined in a prospective, cross-sectional, multicenter study in April 2015. The study aimed to analyze MRSA molecular epidemiology, estimate overall SA infection incidence (MSSA, MRSA, and genotypes) in community-onset (CO: HACO, Healthcare-Associated-CO and CACO, Community-Associated-CO) and healthcare-onset (HO: HAHO, Healthcare-associated-HO) infections, stratified by age groups. Additionally temporal evolution was estimated by comparing this study´s (2015) incidence values with a previous study (2009) in the same region. Erythromycin-resistant-MSSA and all MRSA strains were genetically typed. The SA total-infections (TI) overall-incidence was 49.1/100,000 monthly-visits,