CHITOSAN-BASED NANOCOMPOSITES: PROMISING MATERIALS FOR DRUG DELIVERY APPLICATIONS

ONNAINTY R.; GRANERO G.; ALEX GRUMEZESCU

Biomedical Applications of Nanoparticles

Elseiver

Año: 2018; p. 1 - 34

There is an increasing interest of using bionanocomposites composed of natural biopolymers and mineral clays as promising materials in bionanotechnology. Chitosan (CS) and mineral clays are renewable friendly materials owing their properties of biocompatibility, biodegradability and low toxicity. These advantageous properties, among others, make the CS-based bionanocomposites in extremely interesting materials for a variety of applications, including drug delivery and medical and pharmaceutics aims. This chapter provides an overview of the most important processing strategies and characterization methods, as well as aspect related to their mucoadhesive, biopharmaceutics and drug release behaviors as requirements like nanocarriers for controlled and targeted drug delivery systems.