Prostate epithelial cells are susceptible to and play a major role in innate immunity to Chlamydia muridarum infection, recruiting intracellular TLR4, TLR2 and MyD88 around the inclusion.

AMER SOC MICROBIOLOGY

Año: 2006 p. 6973 - 6973

b> Although Chlamydia infections are widespread throughout the world, data about immunopathogenesis of genitourinary tract infections in males are very limited. In the present work we present an in vitro model of male genital tract-derived epithelial cells, more precisely prostate epithelial cells (PEC), to analyze if they are susceptible and able to respond to Chlamydia muridarum infection. Our results demonstrate that rat PEC are susceptible to