Innate immunity in the male genital tract: Chlamydia

JUAN PABLO MACKERN-OBERTI; MARIANA MACCIONI; MARIA LAURA BRESER; ADRIAN ELEY; THOMAS MIETHKE; VIRGINIA RIVERO

SOC GENERAL MICROBIOLOGY

Año: 2011 vol. 60 p. 307 - 307

font face="AdvP4AD05C" size="1"> Chlamydia trachomatis is an intracellular pathogen that infects mucosal epithelial cells, causing persistent infections. Although chronic inflammation is a hallmark of chlamydial disease, the proinflammatory mechanisms involved are poorly understood. Little is known about how innate immunity in the male genital tract (MGT) responds to C. trachomatis. Toll-like receptors (TLRs) are a family of receptors of the innate immunity that recognize different pathogen-associated molecular patterns (PAMPs) present in bacteria, viruses, yeasts and parasites. The study of TLR expression in