Mast cells in accessory glands of experimentally induced prostatitis in male

RIVERO VE; IRIBARREN P; RIERA CM

Elsevier

Año: 1995 vol. 74 p. 236 - 236

e studied the histological modifications in the accessory glands of autoimmunerats. Adult male Wistar rats were id immunized three times with saline extract ofrat male accessory glands (RAG) chemically modified (MRAG) in complete Freund´sadjuvant (CFA) (groups 1, 2, and 3). Prior to the first immunization withMRAG-CFA groups 2 and 3 received peritoneal cells obtained from rats that hadbeen injected 2 or 24 hr previously with low doses of RAG. Furthermore, anadditional group (group 4) ip immunized with liposome-associated-RAG wasincorporated. The delayed-type hypersensitivity response studied 10 or 15 daysafter first immunization was positive for rats of groups 1, 3, and 4, while itwas negative for rats of group 2. Serum samples obtained on Day 45 and studied byELISA showed high levels of autoantibodies in groups 1 and 2 and lower levels of autoantibodies in group 3, but did not show autoantibodies in group 4. Theh