Chlamydia trachomatis infection of the male genital tract: An update

MACKERN-OBERTI JP; MOTRICH RD; BRESER ML; SÁNCHEZ LR; CUFFINI C; RIVERO VE

ELSEVIER IRELAND LTD

Lugar: Amsterdam; Año: 2013 vol. 100 p. 37 - 37

hlamydia trachomatis (CT) is the most prevalent cause of sexually transmitteddiseases. Although the prevalence of chlamydial infection is similar in men andwomen, current research and screening are still focused on women, who develop themost severe complications, leaving the study of male genital tract (MGT)infection underrated. Herein, we reviewed the literature on genital CT infection with special focus on the MGT. Data indicate that CT certainly infects different parts of the MGT such as the urethra, seminal vesicles, prostate, epididymis and testis. However, whether or not CT infection has detrimental effects on malefertility is still controversial. The most important features of CT infection areits chronic nature and the presence of a mild inflammation that remainssubclinical in most individuals. Chlamydia antigens and pathogen recognitionreceptors (PRR), expressed on epithelial cells and immune cells from the MGT,