MRSA dynamic circulation between the community and the hospital setting: New insights from a cohort study

BARCUDI, DANILO; SOSA, EZEQUIEL J.; LAMBERGHINI, RICARDO; GARNERO, ANALÍA; TOSORONI, DARIO; DECCA, LAURA; GONZALEZ, LILIANA; KUYUK, MARÍA A.; LOPEZ, TERESA; HERRERO, IVANA; CORTES, PAULO; FIGUEROA, MYRIAN; EGEA, ANA L.; GAGETTI, PAULA; FERNANDEZ DO PORTO, DARÍO A.; CORSO, ALEJANDRA; TURJANSKI, ADRIÁN G.; BOCCO, JOSÉ L.; SOLA, CLAUDIA

THE JOURNAL OF INFECTION.

W B SAUNDERS CO LTD

Año: 2020 vol. 80 p. 24 - 24

0163-4453

issemination of methicillin-resistant-Staphylococcus aureus/(MRSA) is a worldwide concern both in hospitals [healthcare-associated-(HA)-MRSA] and communities [community-associated-(CA)-MRSA]. Knowledge on when and where MRSA colonization is acquired and what clones are involved is necessary, to focus efforts for prevention of hospital-acquired MRSA-infections.Methods: A prospective/longitudinal cohort study was performed in eight Argentina hospitals (Cordoba/ October-December/2014). Surveillance cultures for MRSA (nose-throat-inguinal) were obtained on admission and at discharge. MRSA strains were genetically typed as CA-MRSAG and HA-MRSAG genotypes.Results: Overall, 1419 patients were screened and 534 stayed at hospital for ≥3 days. S. aureus admission prevalence was 30.9% and 4.2% for MRSA. Overall MRSA acquisition rate was 2.3/1000 patient-days-at-risk with a MRSA acquisition prevalence of 1.96% (95%CI: 1.0%-3.4%); 3.2% of patients were discharged back to community with MRSA.