In-vitro activity of new sulphanilyl fluoroquinolones against Staphylococcus aureus

DANIEL ALBERTO, ALLEMANDI; FABIANA L. ALOVERO; RUBEN HILARIO, MANZO

OXFORD UNIV PRESS

Lugar: Birmingham (UK); Año: 1994 vol. 34 p. 261 - 261

pTwo new quinolones, NSFQ-104 and NSFQ-105, derivatives of ciprofloxacin and norfloxacin with a 4-(4-aminophenylsulphonyl)-1-piperazinyl at position 7 showed better in-vitro activity against strains of methicillin-susceptible and methicillin-resistant Staphylococcus aureus than ciprofloxacin or norfloxacin. Their in-vitro activity was enhanced at pH 5·5.