Erythromycin A as supramolecular receptor: Association with dyes.

MÓNICA BARRA; MARIANA ADELA FERNÁNDEZ; RITA HOYOS DE ROSSI

TAYLOR & FRANCIS LTD

Lugar: Amsterdam; Año: 1996 vol. 7 p. 137 - 137

span style="LINE-HEIGHT: 115%; FONT-FAMILY: "Calibri","sans-serif"; FONT-SIZE: 11pt; mso-ansi-language: EN-US; mso-fareast-font-family: Calibri; mso-bidi-font-family: "Times New Roman"; mso-fareast-language: EN-US; mso-bidi-language: AR-SA" lang="en">Several organic compounds, such as p-methyl, o-methyl red, p-nitroaniline, sulforhodamine B and rhodamine 6G form molecular complexes in non-aqueous solutions with the antibiotic erythromycin A (E). The association constants for these complexes were determined by spectrophotometric titrations. Enthalpies and entropies of complexation in chloroform were calculated from the temperature dependence of the association constants. The association process appears to be mainly entropy controlled. In chloroform solution p-methyl red associates with E while o.methyl red does not. On the other hand both compounds show a weak interaction in dioxane. The differences in behaviour in the two solvents are attributed to a chen