Huperzia saururus, Activity on Synaptic Transmition in Hippocampus

ORTEGA MARÍA GABRIELA, VALLEJO MARIANA, CABRERA JOSÉ LUIS, PÉREZ MARIELA, ALMIRÓN ROMINA, RAMÍREZ OSCAR, AGNESE ALICIA MARIEL.

JOURNAL OF ETHNOPHARMACOLOGY

Elsevier

Año: 2006 vol. 104 p. 374 - 374

0378-8741

p class="MsoNormal" style="MARGIN: 0cm 0.9pt 0pt 27pt; TEXT-ALIGN: justify; tab-stops: 27.0pt">Huperzia saururus (cola de quirquincho) is used in folk medicine to improve memory. The cholinergic neurons of the basal forebrain, including those in the medial septum, the vertical limbs of the diagonal band of Broca and the nucleus basalis of Meynert provide a major source of cholinergic enervation of the cortex and hippocampus. These neurons have also been shown to play an important role in learning and memory processes. Thus, the effects of this traditional Argentinean species were studied in relation to its activity on synaptic transmition in hippocampus. The alkaloid extract obtained first by d