New insights into the modulation of immune response by Fasciola hepatica excretory-secretory products.

CERVI L., SERRADELL M, GUASCONI L., AND MASIH DT.

Current immunology review

Bentham Science Publishers,

Lugar: United Arab Emirates; Año: 2009 vol. 5 p. 277 - 277

1573-3955

p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; TEXT-ALIGN: justify">Abstract Fasciola hepatica is a trematode that affects human and domestic ruminant health, causing significant economic losses in cattle estimated at US$2000 millon per year. Juvenile parasites migrating through the host tissues, as well as adults settle in the biliary ducts, are in contact with different cells from the immune system. Despite those interactions, the persistence of the parasite in the host for many years provides evidence of its ability to prevent or down-modulate the inflammatory response in