Artículos
Título:
Immunization of rats against Fasciola hepatica using crude
Autor/es:
LAURA CERVI, JANINA BORGONOVO, MARIELA EGEA, LAURA CHIAPELLO, DIANA MASIH*
Revista:
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
Referencias:
Año: 2004 vol. 97 p. 97 - 97
Resumen:
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Chronic Fasciola hepatica infection is correlated with the development of a T helper (Th2)-predominant immune response. To
determine whether immunostimulatory CpG-containing oligodeoxynucleotides (CpG-ODN) or Freund?s complete adjuvant
(FCA), known to promote a Th1 (T helper 1) immune responses, could provide protection from F. hepatica infection, total
homogenate (TH) of F. hepatica mixed with CpG-ODN or FCA were injected subcutaneously (s.c.) into Wistar rats. A F.
hepatica-specific Th1-predominant immune response was induced with CpG-ODN or FCA in lymph nodes of immunized