Differential activation of peritoneal cells by subcutaneous treatment of rats with cryptococcal antigens.

BARONETTI, JL; CHIAPELLO, LS; GARRO, AP; MASIH, DT

CLINICAL AND VACCINE IMMUNOLOGY

American Society of Microbiology

Año: 2009 vol. 16 p. 1213 - 1213

1556-6811

b> Previous studies in our laboratory have shown that the subcutaneous pretreatment of rats with heat-killed cells (HKC) of Cryptococcus neoformans emulsified in complete Freund adjuvant (CFA) promotes protective immunity against an intraperitoneal challenge with C. neoformans. In contrast, subcutaneous treatment with the capsular polysaccharide (PSC) emulsified in CFA exacerbates the cryptococcal infection. The purpose of this study was to analyze the m