The biocompatible polysaccharide chitosan enhances the oral tolerance to type II collagen

PORPORATTO C; CANALI M.M.; BIANCO I.D.; CORREA S.G.

WILEY-BLACKWELL PUBLISHING, INC

Año: 2009 vol. 155 p. 79 - 79

span lang="en" style="font-size: 10pt; font-family: "Times New Roman";">Chitosan is a mucoadhesive polysaccharide that promotes the transmucosal absorption of peptides and proteins. At mucosal sites chitosan exhibits immunomodulatory activities and stimulates the release of regulatory cytokines.  Herein we evaluated the effect of the co-administration of chitosan in the tolerance to type II collagen (CII) using an e