Cryptococcus neoformans and Cryptococcus gattii genes preferentially expressed during rat macrophage infection

LETÍCIA GOULART*; LÍVIA KMETZSCH ROSA E SILVA; LAURA CHIAPELLO; CAROLINA SILVEIRA; JULIANA CRESTANI; DIANA MASIH; MARILENE HENNING VAINSTEIN

TAYLOR & FRANCIS LTD

Lugar: Oxford; Año: 2010 vol. 48 p. 932 - 932

i> Cryptococcus neoformans and Cryptococcus gattii are encapsulated yeast agents of cryptococcosis and facultative intracellular pathogens. The interaction of these yeasts with macrophages is essential for containing the infection. However, Cryptococcus spp. overcome this initial host defense barrier using a unique pathogenic strategy involving intracellular replication a