Inhibition of I-A expression in rat peritoneal macrophages due to T-suppressor cells induced by Cryptococcus neoformans.

MASIH DT, SOTOMAYOR CE, CERVI LA, RIERA CM, RUBINSTEIN HR.

MYCOPATHOLOGIA

Año: 1991 vol. 29 p. 125 - 125

0301-486X

p class="MsoNormal" style="MARGIN: 12pt 0cm 0pt 42pt; LINE-HEIGHT: 14.4pt">The expression of I-A antigen in rat peritoneal cells was significantly reduced during infection with Cryptococcus neoformans. When studying the in vitro action of T-suppressor cells induced by the fungus, or a soluble factor from the T-suppressor cells, a significant decrease in I-A expression by the peritoneal cells was observed. This expression was partially restored by indomethacin.