Effect of the parental origin of the X-chromosome on the clinical features, associated complications, the two-year-response to growth hormone (rhGH) and the biochemical profile in patients with turner syndrome

FRANCISCO ALVAREZ-NAVA; ROBERTO LANES; JOSE MIGUEL QUINTERO; MIRTA MIRAS; HUGO FIDELEFF; VERONICA MERICQ; HENRY MARCANO; WILLIAM ZABALA; MARISOL SOTO; TATIANA PARDO; LISBETH BORJAS; JOALICE VILLALOBOS; PETER GUNCZLER; NANCY UNANUE; NATALIA TKALENKO; ADRIANA BOYANOFSKY; LILIANA SILVANO; LILIANA FRANCHIONI; MIRIAM LLANO; GABRIEL FIDELEFF; MIRIAM AZARETZKY; MARTHA SUAREZ

International Journal of Pediatric Endocrinology

Springer-Verlag GmbH

Lugar: Heidelberg; Año: 2013 vol. 10 p. 1 - 1

font size="2" face="AdvTT99c4c969"> Background: It is possible that genes on the X chromosome are expressed differently depending of its parental origin. The objective of this study was to determine the influence of the parental origin of the X-chromosome on phenotypic variability, response to rhGH and on the biochemical profile of TS patients.It is possible that genes on the X chromosome are expressed differently depending of its parental origin. The objective of this study was to determine the influence of the parental origin of the X-chromosome on phenotypic variability, response to rhGH and on the biochemical profile of TS patients. Methods: